ArthritoMab Antibody Cocktail for Inducing Arthritis in the Collagen Antibody Induced Arthritis Model
versatility of strains with the ArthritoMab Antibody Cocktail and the Collagen Antibody induced arthritis model
 
ArthritoMab Antibody Cocktail Advantages to the CAIA model Epitope Specificity Versatility in Strains
       
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  ArthritoMab antibody cocktail for induction in the Collagen Antibody Induced Arthritis model  
         
 

Versatility of Collagen Antibody Induced Arthritis (CAIA)

Unlike the Collagen-Induced Arthritis (CIA) model which requires a restricted MHC haplotype thereby limiting the available strains, the CAIA model using ArthritoMab™ Antibody Cocktail can be used in various strains including CIA-resistant, gene-knockouts and transgenic animals.

Commonly used strains in the CAIA model:

  •  
    • DBA/1
    • Balb/c
    • B10.RIII
    • B10.Q
    • C57Bl/6

 

Histology in various strains in the Collagen Antibody Induced Arthritis model

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ArthritoMab whitepaper

 
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